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When Sean Watanabe's girlfriend Theresa was killed by the Mandarin during "Acts of Vengeance", he vowed revenge on all involved. Brass teamed up with Wolverine and Ghost Rider (Ketch) against Deathwatch.
Creator of the machines that hunt mutants known as the Sentinels.
Aria is an alien, from the Zennan nation.
A Kamikaze pilot who survived but was horribly scarred, Lord Dark Wind became obsessed with restoring his honor.
Member of Landau, Luckman, and Lake.
A precognitive member of Landau, Luckman & Lake
Orphan Maker is an enigmatic mutant, whose powers (though unrevealed) remained after Decimation. As a boy, he was nearly killed by Mr. Sinister. Nanny rescued & recruited him for her team, the "Lost Boys." He kills the parents of mutant children, creating more soldiers for Nanny.
Aldo Ferro was employed by the Weapon X project to telepathically implant it's members with false memories.
General Coy is a crime boss in Madripoor.
William Stryker was a U.S. soldier who, after learning his child was a mutant, murdered his family and became a religious extremist and founded the Purifiers whose sole mission was to exterminate all mutants.
When Master Mold subsumed Nimrod, the resulting robot was forced into the Siege Perilous by the X-Men. Once, a mysterious man named Bastion saw himself as humanity's last "bastion" of hope, unaware of his identity as a Sentinel.
The Primogenitor was the original Mandate created by scientists in the year 2047 to kill the toxins that covered the Earth.
Daken is Wolverine's long lost son, torn from his mother's womb by the dark figure Romulus. Raised with a warped view on his father's "abandonment" and his mother's murder, Daken was left holding a grudge.
An extremely resilient bio weapon created by the Deviants that could consume and absorb its enemies growing in power
Lazaer is seen every time Wolverine has a near-death experience. Wolverine talks about having to fight Lazaer for his life every time this happens. Lazaer uses a huge sword to fight with. Wolverine seems to have killed Lazaer when they were both alive.
Scotsman killer, was an associate of Wolverine.
Matthew Risman is the leader of the Purifiers, an extremist cult which seeks the eradication of all mutants. He is the successor of the late William Stryker, who founded the Purifiers.
Muramasa is an excellent skillful smith of a violent and somewhat insane mind. All of his swords are extremely sharp which are bolstered through his the ability to put souls in his weapons making them infinitely more effective, and lethal. These soul blades hunger for the will of the soul used to make it.
A mysterious woman who Wolverine meets in Madripoor, who attempts to seduce him, she is actually a mutant psychic vampire who sadistically drains the Life-Forces of innocent people with no remorse for her actions.
Eli Bard was a former politician from ancient Rome that became obsessively in love with the immortal Selene. After failing her in her ascension, she cursed him and since then, he has been finding ways to gain the Black Queen's favor back.
Psychic Demon who feeds on Suffering and Misery
Doombringer is an enemy of Wolverine and the Silver Samurai. It is an extra-dimensional beast, summoned to Earth to destroy it.
Charlemagne was the codename of a skilled mercenary and assassin. She was one of Wolverine's best friends during his days in espionage. She was killed by Spider-Man accidentally.
Warlord of the extradimensional realm of Kageumbra
An immensely powerful alien warlord, Horde seeks out the X-Men and challenges them with a task, that will secretly result in him gaining even more power.
Giant worm-like monstrous creature-demon from Lakota myths.
Founding member of the Brotherhood of Evil Mutants, Jason Wyngarde was the original Mastermind. He was instrumental in the creation of Dark Phoenix, ruining Wolverine's relationship with Mariko Yashida and later died of the Legacy Virus. His two daughters have inherited his telepathic illusionary powers and name.
A charming master thief and skilled martial artist who became a member of the X-Men, Gambit possesses the mutant ability to change potential energy in inanimate objects into kinetic energy which causes them to explode. His signature move is throwing kinetically-charged playing cards at his opponents.
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