During the 1940s, the island was used as a staging ground for a top secret research facility called Project Moreau. Project Moreau was a precursor to the modern age Project Cadmus. One of their scientists, Doctor Grant, was responsible for conducting experiments that evolved normal animals into higher-order life forms colloquially known as "Furries". The Furries eventually developed their own culture and social/political hiearchy. The project went bad when the Furries were apparently going to be used for violent means, which lead to the so called "Beast Wars". Grant managed to hide all knowledge of the island from the rest of the world and entrusted the serpentine Sacker to use his serum on any humans that arrived on the island.
The dominant race of Furries were the Tigers who established the capital city of Roam. Over the course of several decades, the Roaman monarchy was dominated by the tiger bloodline. In the modern era, the Wild Lands was governed by Great Caesar, a veteran of the Beast Wars. Caesar's nemesis was the evil bat-woman known as Nosferata, who operated in secret from within her private cave, and implanted one of her own agents, the treacherous, Ratsputin, into Caesar's royal council.
Over the span of several years, Sacker established a trading post for himself and maintained a stock of human slaves. He used a special serum that made the humans mute, and diminished their intellect. Because of this, everyone in the Wild Lands thought that humans were by nature, dumb, savage animals.
A few years ago, Sacker sold an old energy weapon to some gorilla soldiers. They tested it by firing it into the sky and the blast struck the teen-hero Superboy, who had just happened to have been flying near that area. The blast temporarily took away Superboy's powers and memories. He was captured by Sacker and put to work as a slave, but he soon escaped and came into the possession of Prince Tuftan, son of Great Caesar.
Superboy's memories and powers quickly returned and he aided Tuftan and the Wild Men against the forces Nosferata, Sacker and the gorilla soldier known as Killa. Nosferta however, succeeded in having Great Caesar murdered, and blackmailed Prince Tuftan into marrying her, thereby making her queen of the Wild Lands.