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Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
The clone of May Parker (Spider-Girl). She was biologically reengineered to be a symbiote hybrid. After naming herself April in order to interact with ordinary life, she gave herself the name Mayhem to operate under in her superhuman activities. April dies in a building explosion while fighting Spider-Girl.
The Son of Black Tarantula and Black Tarantula himself in MC2 universe.
Mary Jane Watson is an actress and a major love interest of Peter Parker aka Spider-Man. They have had a long and dramatic on-and-off-again relationship. She's one of the few people who know who he is and still supports him as a close friend and confidante.
The daughter of Peter Parker, the original Spider-Man, May "Mayday" Parker continues her father's legacy as the Spider-Woman of Earth-982 (MC2 Universe).
Anya Sofía Corazón is a 17 year old super-heroine who originally went by the name Araña and had a symbiotic exoskeleton which emanated from her spider-shaped tattoo. She then lost those powers and instead gained new powers similar to that of Spider-Man. Anya currently goes by the name of Spider-Girl.
Don Silvio aka Silverback is an old crime boss.
A talented artist, who has collaborated with Jimmy Yama in producing a Spider-Girl comic. He began a short relationship with Davida Kirby, but Davida begins to suspect his true feelings are for May and encourages him to tell her how he feels. The two are currently dating.
A man who would later take the name of Martin Li, was given an experimental drug which eventually allowed him control of some type of black electrical energy resembling a photographic negative.
Davida Kirby is May Parker's best friend in the MC2 universe.
Classmate of May "Mayday" Parker a.k.a. Spider-Girl.
Member of a crime family in South America, she is a constant foe of both Normie Osborn and Spider-Girl. She is in the MC2 universe.
Son of Flash Thompson and boyfriend to May "Mayday" Parker (Spider-Girl).
Small time thug who gained super-strength, and eventually terminal illness, through abusing an experimental horse steroid.
Kaine was the first clone of Spider-Man created by the Jackal. He was suffering from clone degeneration and became an assassin and spent years tormenting his clone brother, Ben Reilly. He has since taken up the mantle his now dead brother as the new Scarlet Spider.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
Jackpot is a new registered hero with The Initiative who fights in New York City. There have been two people to take the Jackpot identity, Alana Jobson who died, and first and current heir Sara Ehret.
The son of Peter Parker and Mary Jane. He possesses abilities similar to his father and older sister, Mayday, and has recently been moonlighting as his sister's sidekick.
The son of Ben Reilly and Elizabeth Tyne, Darkdevil has proven to be a tempestuous ally of his "cousin" Spider-Girl. His powers stem from his biological inheritance, as well as the souls of Daredevil and Zarathos.
Leader of a gang called Dragon Lords in Chinatown in NYC. He is a master of the martial arts.
Former pro baseball player who became a known criminal as the Boomerang. After fighting towards some semblance of redemption as a member of the Thunderbolts, he lead the seventh incarnation of the Sinister Six.
The second and most successful clone of Spider-Man created by the Jackal. A superhero known as the Scarlet Spider, Reilly later replaced Peter Parker for a time as Spider-Man after he found out that all this time he was the original and not Peter. Ben met his ultimate demise in the fight against the Green Goblin which led to Peter becoming Spider-Man once again, after he found out that he is the real Spider-Man after all.
Rigger Ruiz is an army member of Code Blue
Extremist doesn't like the gray world, he likes it black and white.
A fellow student of May (Spider-Girl) Parker. She has a bit of an...attitude. She is also the daughter of Rene DeSantos, who is a member of the Goblin Cult.
Member of the Repo Squad. Wears a variation of the Beetle armor.
Dr. Stephen Strange was once a gifted but egotistical surgeon who sought out the Ancient One to heal his hands after they were wounded in a car accident. Instead, the Ancient One trained him to become Master of the Mystic Arts and the Sorcerer Supreme of Earth.
Jimmy Yama is a student at Midtown High and is a longtime and close friend to May "Mayday" Parker a.k.a. Spider-Girl. He also the cousin of Zane Yama a.k.a. J2, the son of the Juggernaut.
Former cat burglar Felicia Hardy became a crime fighter when she became romantically attracted to and involved with Spider-Man. Felicia has the ability to instill "bad luck" around others - this comes in handy when fighting crime!
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