Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, which he could have prevented, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became the Amazing Spider-Man!
The daughter of Peter Parker, the original Spider-Man, May "Mayday" Parker continues her father's legacy as the Spider-Woman of Earth-982 (MC2 Universe).
Mary Jane Watson is a major love interest of Peter Parker aka Spider-Man. She married him but didn't(!), now she's one of the few people who know who he is, and still supports him as a close friend and confidante. Currently, Mary Jane and Peter have reconciled their relationship and she no longer seems to work for Stark Industries.
The Son of Black Tarantula and Black Tarantula himself in MC2 universe.
The possible clone of May Parker (Spider-Girl). She was biologically reengineered to be a symbiote hybrid. After naming herself April in order to interact with ordinary life, she gave herself the name Mayhem to operate under in her superhuman activities. April dies in a building explosion while fighting Spider-Girl.
Anya Sofía Corazón is a 17 year old super-heroine who originally went by the name Araña and had a symbiotic exoskeleton which emanated from her spider-shaped tattoo. She then lost those powers and instead gained new powers similar to that of Spider-Man. Anya currently goes by the name of Spider-Girl.
A talented artist, who has collaborated with Jimmy Yama in producing a Spider-Girl comic. He began a short relationship with Davida Kirby, but Davida begins to suspect his true feelings are for May and encourages him to tell her how he feels. The two are currently dating.
Don Silvio aka Silverback is an old crime boss.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
Classmate of May "Mayday" Parker a.k.a. Spider-Girl.
Davida Kirby is May Parker's best friend in the MC2 universe.
Kaine was the first clone of Spider-Man created by the Jackal. He was suffering from clone degeneration and was used as a test subject until he fled. He became an assassin and spent years tormenting his clone brother Ben Reilly until he was eventually cured of his cellular degeneration and has taken up the mantle his now dead brother as the new Scarlet Spider.
Small time thug who gained super-strength, and eventually terminal illness, through abusing an experimental horse steroid.
Son of Flash Thompson and boyfriend to May "Mayday" Parker (Spider-Girl).
Member of a crime family in South America, she is a constant foe of both Normie Osborn and Spider-Girl. She is in the MC2 universe.
A man who would later take the name of Martin Li, was given an experimental drug which eventually allowed him control of some type of black electrical energy resembling a photographic negative.
The second and most successful clone of Spider-Man created by the Jackal. A superhero known as the Scarlet Spider, Reilly later replaced Peter Parker for a time as Spider-Man after he found out that all this time he was the original and not Peter. Ben met his ultimate demise in the fight against the Green Goblin which led to Peter becoming Spider-man once again, after he found out that he is the real Spider-man after all.
Former pro baseball player who became a known criminal as the Boomerang. After fighting towards some semblance of redemption as a member of the Thunderbolts, he lead the seventh incarnation of the Sinister Six.
The son of Ben Reilly, Darkdevil has proven to be a tempestuous ally of his "cousin" Spider-Girl. His powers stem from his biological inheritance, as well as the souls of Daredevil and Zarathos.
Leader of a gang called Dragon Lords in Chinatown in NYC. He is a master of the martial arts.
In the MC2 universe, the son of Peter and Mary Jane Parker and brother to Spider-Girl.
A fellow student of May (Spider-Girl) Parker. She has a bit of an...attitude. She is also the daughter of Rene DeSantos, who is a member of the Goblin Cult.
Jackpot is a new registered hero with The Initiative who fights in New York City. There have been two people to take the Jackpot identity, Alana Jobson who died, and first and current heir Sara Ehret.
Rigger Ruiz is an army member of Code Blue
Extremist doesn't like the gray world, he likes it black and white.
Dr. Stephen Strange was once a gifted but egotistical surgeon who sought out the Ancient One to heal his hands after they were wounded in a car accident. Instead, the Ancient One trained him to become Master of the Mystic Arts and the Sorcerer Supreme of Earth.
Former cat burglar Felicia Hardy became a crime fighter when she became romantically attracted to and involved with Spider-Man. Felicia has the ability to instill "bad luck" around others - this comes in handy when fighting crime!
Flash attended the same high school and university as Peter Parker, who would later be known as Spider-Man. He frequently bullied Peter but was actually Spider-Man's greatest fan. In time Flash befriended Peter, becoming a decorated war hero and was bonded to the Venom symbiote. Some time after losing the symbiote, Flash became the new Anti-Venom.
Secretary to J. Jonah Jameson.
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