These protectors have almost unlimited powers to control the time. Their only goal is to preserve their existence, so the universe can stay in peace. It is because of this that they have had faced both heroes and villains such as the Avengers and the Scarlet Witch. For some time, they recruited Immortus in order to destroy the Avengers because the Time Keepers feared the expansion of humanity all over the space could be dangerous.
Finally, the Time Keepers decided to destroy all the alternative realities so they could remain as the only time guardians. Then, the time traveler Kang asked Rick Jones (Captain Marvel) if he could aid him to save the other realities. Rick accepted and they both managed to defeat the Time Keepers. During the battle, they seemed to die, but it is unknown if they really are dead.