Puma is a powerful Native-American Werecat. Puma was raised to fight the Beyonder and became an ally to Spider-Man.
During an experiment Dr. Curtis Connors accidentally turned into a ferocious reptilian monster who seeks to turn humans into lizards like himself. The Lizard is one of Spider-Man’s oldest and deadliest foes while ironically, his alter ego is a close friend and former teacher of Spidey’s alter ego Peter Parker.
Lance Bannon was a former rival photographer of Peter Parker and boyfriend to Amy Powell. He was later murdered by the man known only as F.A.C.A.D.E.
As a child, Matt Murdock was blinded by radioactive waste while trying to save an elderly stranger about to get hit by a truck carrying the dangerous material. In turn, his other senses were heightened to superhuman sharpness and he gained a form of "radar sense". By day, he is a successful trial lawyer; but by night, he guards Hell's Kitchen as Daredevil: the Man Without Fear.
A retired vaudevilian and love interest to Aunt May. He was also friends with Adrian Toomes, the original Vulture.
Mamie Muggins was the landlord of Peter Parker (Spider-Man) in the 1970's and early1980's
The first true love of Peter Parker. She's best known for her tragic death by being thrown off from the Brooklyn Bridge by the Green Goblin. The Earth-65 version is Spider-Gwen who is a major player in the Spider family.
Jean DeWolff is a New York cop and ally of Spider-Man. Her brother, Brian DeWolff, was the troubled villain/vigilante known as "The Wraith".
Peter Parker's uncle and the father figure whose death was the main inspiration for Peter becoming Spider-Man. Ben Parker taught Peter that with great power comes great responsibility.
John Jameson is an astronaut, a test pilot and for his father J. Jonah Jameson the archetype of a true hero unlike these “masked clowns” like Spider-man. John has also been transformed into a Werewolf-like creature called the Man-Wolf, and was once host to the Carnage Symbiote.
Edward Whelan was transformed by the second Baron Zemo into the hideous, beastly, rat creature that he is today.
Roderick Kingsley became a worthy heir of the Goblin legacy, creating his own identity, of the Hobgoblin, rather than being just another Green Goblin clone.
After his family was killed by the mob, U.S. Marine Special Forces veteran Frank Castle vowed to avenge their deaths and became a one-man army in his personal war against the criminal underworld. With a distinct death's head skull adorning his chest, Frank Castle became the vigilante known as the Punisher.
Personal assistant to the Kingpin, oversaw various criminal operations.
The Venom symbiote bonded with Spider-Man during his adventure in the first "Secret Wars" on the Beyonder's makeshift planet called Battleworld. Initially, he thought the symbiote was just a costume. However upon his discovery that it was sentient, he rejected it. Since then, the symbiote has bonded with several different hosts. It's current host is Eddie Brock.
Dmitri Smerdyakov, AKA Chameleon, was first member of an inexperienced Spider-Man's rogue's gallery. The Chameleon is an elite spy and a master of disguise, using a variety of masks, technology, and other inventive techniques to flawless mimic the appearance and mannerisms of virtually anyone. Although he has been revealed to be the half-brother of Kraven The Hunter, the face behind his trade-mark white mask – worn even beneath his other masks – has never been seen.
The Jackal is an enemy of Spider-Man who played a big role in both of the Clone Sagas. He has since seemingly returned to infest Manhattan with spider-powers for his own sinister ends, organizing test subjects into a spider-powered army.
Peter Parker's friend since college and Robbie Robertson's son.
Tyrone Johnson is the "dark" half of the vigilante duo known as Cloak and Dagger. After a drug-related experiment awakened his powers, he became a living personification of darkness. Cloak is the Yin to his partner Dagger's Yang. Superheroes of the streets, Cloak and Dagger wage a war against dangerous drugs and drug-related crimes.
A power-hungry crime lord who has been a regular opponent of Daredevil and Spider-Man.
Martha Robertson is the wife of Robbie Robertson, former editor at the Daily Bugle and mother of Randy.
A former photographer of Daily Bugle and one of the biggest sleaze-bags you could ever hope to meet.
NYPD swat team leader who is not too fond of Spider-Man.
The ex-boyfriend of Debra Whitman.
During World War II, Steve Rogers volunteered to receive the experimental Super-Soldier Serum. Enhanced to the pinnacle of human physical potential and armed with an unbreakable shield, he became Captain America. After a failed mission left him encased in ice for decades, he was found and revived by the Avengers. Later joining their ranks and eventually becoming the team's leader.
Tandy Bowen is the "light" half of the vigilante duo known as Cloak & Dagger. After a drug-related experiment awakened her powers, she became a living personification of light, with the ability to generate super-luminosity at will and use it both offensively and defensively.
Reed Richards, also known as Mr. Fantastic, is the leader of the Fantastic Four. He can stretch his body to great distances due to his exposure to cosmic rays while in space. He is also considered to be one of the smartest men alive, using his brain to explore alternate dimensions and save the world alongside his family from science-based threats.
Ex-wife of Randy Robertson.
The second most powerful member of the Fantastic Four and the younger brother of Sue Richards. Due to an accident caused by cosmic radiation in space, he can manipulate fire, turn his entire body into it and fly. While Johnny is known for his impetuous and sometimes reckless nature, he is also a loyal friend and fearless hero.
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