Contains reprinted material that originally appeared in the newspapers and were later put into trade paperback format.
- Foreword by Gary Larson.
- "Part 1: Origin of the Species"
- "The Fossil Record"
- "Part 2: Evolution"
- "Creative Process"
- "Sketchbook Sampler"
- "Stories"
- "Part 3: Mutations"
- "Mistakes (Mine and Theirs)"
- "Subtle Things"
- "Part 4: Stimulus-Response"
- "Public Response"
- "Rejected Comics"
- "Part 5: The Exhibit"
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