The first appearance of Rogue! Ms. Marvel lies disoriented and weakened after her powers are absorbed by Rogue. Will Spider-Woman be able to restore her amnesiac friend? Just as the Avengers band together to take care of their fallen teammate, the Brotherhood of Evil Mutants attack!
First appearance of Rogue and an X-Men cameo in "By My Friends ? Betrayed!" Guest-starring Spider-Woman. A sensational action-packed annual of Earth's Mightiest Heroes! Featuring the first appearance of Rogue, the spectacular art of Michael Golden, the tragic return of Carol Danvers, and the tremendous battle between the Brotherhood of Evil Mutants and the mighty Avengers! Following the events of Uncanny X-Men 148.
Four members of Mystique's Brotherhood of Evil Mutants ( Blob, Avalanche, Destiny and Pyro) are inmates at Ryker's Island prison! But before the brotherhood can carry out the prison break, they must trim the ranks of the super-heroes likely to oppose them...the Avengers! The combination of Rogue and Mystique successfully knocks Captain America, Iron Man and Thor out of action! And later on at the stroke of midnight, the jailbreak begins! However, the Avengers and Spider-Woman have been tracking Rogue's movements, and when their quinjet lands at Ryker's Island...the epic clash erupts! Wow!
Then it is Beast, Hawkeye, Jocasta, Scarlet Witch, Vision, Wonder Man and Spider-Woman vs. the Blob, Avalanche, Destiny, Pyro, Mystique, and Rogue! Avengers Assemble! Meanwhile, woven in and around the frantic action at Ryker's Island is the heartbreaking story of Carol Danvers' return to Earth. Her life has fallen apart since leaving for Limbo with Marcus Immortus in Avengers 200. And now stripped of her powers and memories, Carol begins the long road to recovery. And the first step is an emotional confrontation with her former teammates!
- Ranked #65 in Wizard Magazine's list of "100 Best Single Issue Comics Since You Were Born".
- First appearances of Rogue and Madelyne Pryor, who appears in this issue as a toddler at the same hospital Carol Danvers is being admitted to.
- Cameo appearances by Professor Xavier, Colossus, Kitty Pryde, Nightcrawler, Storm and Wolverine.
- Flashback cameo by Marcus Immortus.
- Avengers Lineup: Beast, Captain America, Hawkeye, Iron Man, Jocasta, Scarlet Witch, Thor, Vision and Wonder Man.
- This issue was reprinted and issued with the Marvel Legends figure Wardbird.