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Will Madame Web have the answers Spider-Man is looking for?! Plus, The Black Cat vs Puma and Vermin vs The Lizard!

By Roberto Aguirre-Sacasa and Clayton Crain.

Also: A life of crime may look like a good idea, but not when Spidey is about!

By Tom Mclaughlin and Scott Kolins.

Plus: Spider-Man has come out of retirement, but is he ready for the Sinister Six?

By Kaare Andrews

Includes material reprinted from The Sensational Spider-Man #26, Spider-Man: Reign #2 and Spider-Man Unlimited Vol 3 #3

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