Character » Thanos appears in 1257 issues.
The Annihilation Wave are an army from the Negative Zone.
The Avengers are Earth's mightiest heroes and foremost super-team... "There came a day, a day unlike any other, when Earth's mightiest heroes found themselves united against a common threat. On that day, the Avengers were born - to fight the foes no single super hero could withstand! Heed the call, then - for now, the Avengers Assemble!"
The Cabal is a secret group of criminal masterminds originally assembled by Loki in Acts of Vengeance. Subsequent iterations have been brought together by Red Skull, Norman Osborn during Dark Reign and Namor after Infinity.
Recruited villains to find the Oracle of Ancient Knowledge
The Deviants are an evolutionary offshoot of humanity created by the Celestials' experiments on prehistoric humans around a million years ago.
Thanos is a mutant Eternal of Titan. As such he is powerful enough to be a threat on a galaxy level. It is his cunning and god-like intellect that makes him a universal threat.
Kid Thanos joins a Mutiversal Masters of Evil in Avengers (2018) #50
A group of heroes assembled in differant forms based on the situation. They have been led by Doctor Strange and later Doctor Druid.
In the Holy War storyline, Thanos assembled his own team of Defenders to kidnap and dispose of various intergalactic Messiahs.
Godlike aliens (later retconned as a group of Eternals) who founded a colony on Saturn's Moon Titan, becoming a civilization run by the supercomputer ISAAC and producing Starfox, Mentor, and Thanos.
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