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Max Modell was the head of Horizon Labs and also the employer and good friend of Peter Parker.
The father of Dr. Octopus.
Sha Shan is a Vietnamese national who has saved Flash Thompson’s life many times. After a brief stint as a Spider-Man villian called Sister Sun, she gave up crime.
Ravencroft Sanitarium for the Criminally Insane psychiatrist. She has been the Doctor to Carnage, Shriek, Carrion, Vermin, Chameleon, Massacre and Venom to name a few. Later she becomes the villain called Goblin Queen.
I.C.M. built a computer in the form of a human body in order to dramatize its powers. It was the greatest mechanical brain ever built. It has been recently seen as the newest member of the Sinister Six.
Former New York City Police Department officer and Peter Parker's ex-girlfriend. She was briefly transformed by the Goblin Serum, but has since been returned to normal.
A villain who uses nanites to alter motor vehicles to his liking. Formerly working for Mr. Negative, he is now a member of the Sinister Six.
A journalist who worked at the Daily Bugle along with Peter Parker and after Civil War in Front Line newspaper. She seems to like sarcastic humor and Peter is usually the joke.
The amoral industrialist Norman Osborn was transformed by an experimental serum into the maniacal Green Goblin, and has endured over the decades as Spider-Man's most dreaded archenemy. Osborn is known for being the killer of Gwen Stacy, the architect of the Clone Saga, and the one-time director of S.H.I.E.L.D.
The White Rabbit is a young woman with a dangerous obsession with Lewis Carroll. She is an enemy of Spider-Man.
Uatu is a pre-teen genius who works in Horizon Labs.
Bella is a co-worker of Peter Parker at Horizon Labs.
A new villain whose dangerous methods and utter disregard for human life prompt Spider-Man to don a new armored costume.
A co-worker of Peter Parker's at Horizon Labs.
Sajani worked in Horizon Labs and currently, in Parker Industries. She is the creator of the Reverbium.
Otto Octavius' former classmate and his professor while he was in possession of Peter Parker's body.
A chemistry and physics tutor who offers her help to Otto Octavius/Peter Parker.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
Mary Jane Watson is an actress and a major love interest of Peter Parker aka Spider-Man. They have had a long and dramatic on-and-off-again relationship. She's one of the few people who know who he is and still supports him as a close friend and confidante.
The man who ruled over Nazi Germany during World War II. He wished to wipe leftists, Jews and other "inferiors" from the planet and rule over the world propagating an Aryan race agenda, an ideal that he oddly did not fall into himself.
Secretary to J. Jonah Jameson.
Former pro baseball player who became a known criminal as the Boomerang. After fighting towards some semblance of redemption as a member of the Thunderbolts, he lead the seventh incarnation of the Sinister Six.
Janice Lincoln, daughter to the mobster Tombstone, is the current Beetle, formerly a member of Boomerang's Sinister Six, and now the leader of an all-new Sinister Syndicate.
Shocker is a supervillain originating from Marvel Comics. A self-taught engineer, Herman Schultz created a pair of gauntlets that produces shock waves incorporated into a suit that protects him from the impact of of the blasts. He is a recurring foe of the superhero Spider-Man.
Swindled by his business partner out of his equal share of the profits from their company, Adrian Toomes set out for revenge by using a flying harness of his own design. He has however, met defeat several times at the hands of his arch-nemesis, The Amazing Spider-Man.
Mysterio was a formidable foe to Spider-Man. So much so that his arts of illusion were carried on by others after the original Mysterio's death. The original Mysterio, Quentin Beck, has recently returned. The events behind his resurrection are currently shrouded in mystery.
Former enemy of Spider-Man and the Fantastic Four, Sandman reformed after realising he was unhappy with his life. He joined the Avengers and later Silver Sable's Wild Pack. Sandman eventually returned to crime after being brainwashed by the Wizard, but sometimes still displays desire to better himself.
One of Spider-Man's most dangerous enemies, the electric human dynamo known as Electro has constantly been a major threat for the Amazing Spider-Man.
A famous big game hunter, who became a mercenary and later, developed an intense obsession with restoring honor to his name. Kraven has been known as a major threat for Spider-Man and leaving a legacy during his demise.
James Sanders was a member of the Squadron Sinister known as Whizzer until he pursued a solo life of crime as Speed Demon. He eventually found himself a member of the Thunderbolts despite being unsure if he even wanted to reform.
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