Squirrel Girl appears in 451 issues.
Craving for the power of a Hulk, Emil Blonsky purposely had himself infected with triple the amount of gamma that the Hulk originally had. However, it turned him into a monstrous amphibious reptoid as being originally more than twice the strength of the normal calm Hulk, at the cost of never being human again.
A crook and companion to the Thunderbolt Songbird, after his death, she started a new life as a hero.
Seeking challenges, Arcade has tested the abilities of many superheroes in the Marvel Universe. Trapped inside his dangerous Murderworlds and playing to survive, always nothing more than just a game for Arcade.
A man that has had his head placed on a gorilla's body.
A mystical entity whom encountered Doctor Strange a few times.
Squirrel Girl is mentioned to have defeated Baron Mordo, off-panel.
Mercenary, formerly of the French Foreign Legion. He is one of the most formidable unarmed combatants in the world. He has mastered numerous martial arts and is perhaps the world's leading master of Savate, the French art of kick boxing. He is an accomplished thief and smuggler.
The Bi-Beast is comparable to a combination of Bruce Banner and the Hulk together. Super strong, durable, feral, yet has the intellect of Bruce. This makes the Bi-Beast a dangerous foe.
Super Skrull that battled U.S. Avengers. Possesses the powers of the X-Men.
Jonathan Swift was the second Blue Streak who fought the Heroes for Hire and Thunderbolts.
Former pro baseball player who became a known criminal as the Boomerang. After fighting towards some semblance of redemption as a member of the Thunderbolts, he lead the seventh incarnation of the Sinister Six.
She is a joke character of the marvel universe having beaten Doctor Doom, Thanos, Deadpool and MODOK all with the help of squireel friend Monkey Joe.
Celestial who attacked Earth.
Elder of the Universe and former wielder of the Grandmaster title.
Wade Wilson is a former test subject of the Weapon X program, where he received his regenerative healing factor through the scientific experiments conducted upon him. Deadpool's powers and personality traits combine to make a wild, mentally unstable, and unpredictable mercenary. Deadpool has been a member of X-Force and the Thunderbolts, and a self-professed member of the X-Men and the Avengers. The "Merc with a Mouth" is infamous for breaking the fourth wall.
The herald of Oblivion.
Squirrel Girl defeated the Latverian ruler in her very first appearance trying to convince Iron Man to let her join the Avengers in Marvel Super-Heroes #8. Sadly, Iron Man told her she was too young to join the Avengers (She was just 14!!) and she went on her way (with Dr. Doom's face mask as a trophy!!)
Dr. Sergei Yesenofsky is a mad scientist who attempted to hold the world for ransom with a manufactured virus.
Dormammu is the older twin brother of Umar and Ruler of the Dark Dimension, a being of immense mystical power. He uses his vast powers to conquer other universes and dimensions, earning himself the enmity of Doctor Strange in the process.
Squirrel Girl apparantly has also defeated Ego.
Ember Quade is an Inhuman with the power to bring video games to life.
A Deviant Unlimited Class Wrestling Federation wrestler. He and other members of Delta Force were sent to rescue a group of Avengers from Ghaur.
Long time member of the Enforcers
Squirrel Girl has fought and defeat Fin Fang Foom.
Giganto is a behemoth whale creature summoned by the Horn of Proteus. Namor would call upon Giganto to attack the surface world and the Fantastic Four.
Giganto is one of the Mole Man's pets from Monster Isle. Giganto appears on the cover of the legendary Fantastic Four #1, squeezing the Invisible Girl, who is unable to turn invisible fast enough.
Robot enforcer of the galactic mob. Battled the USAvengers.
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