Jessica Drew was genetically enhanced and given super-powers by the criminal organization HYDRA, for whom she became an assassin as Spider-Woman. She later reformed and became a SHIELD agent and was also once a member of the Avengers and an Agent of SWORD.
Lindsay McCabe is Jessica Drew's (Spider-Woman) best friend. Lindsay also spends time with Wolverine in Madripoor.
Jerry Hunt or Gerald Hunt is an agent of S.H.I.E.L.D stationed in London. After encountering Spider-Woman (Jessica Drew), Jerry takes a extended leave of absence from S.H.I.E.L.D and follows her to Los Angeles, where he becomes Spider-Woman's love interest.
A close friend and ally to Jessica Drew, the Spider-woman. He was bound to a wheelchair, and after some time, his mental condition worsened and he became the mercenary known as the Hornet.
Magnus is a sorcerer, as well as a friend and tutor to Jessica Drew, the Spider-woman. One of his main advisories is Morgan le Fey.
Morgan Le Fay is among the most powerful sorceresses in the history of the Earth. She is a frequent adversary of Spider-Woman, the Avengers, Ian McNee, and Dr. Doom.
The landlord and romantic interest of Jessica Drew, the Spider-woman.
Sabrina "Bree" Morrell was a police lieutenant in San Francisco who frequently worked with Spider-Woman/Jessica Drew. She also had contact with the X-Men and was the one assigned the Carol Danvers case in "Avengers Annual" #10.
After witnessing the murder of his parents in front of him, Maximillian Coleridge vowed to fight crime in any way he could. Initially undercover with a group of villains known as Night Shift, he worked alongside the Avengers, Spider-Woman and Moon Knight.
The Brothers Grimm are two sets of twin supervillains who are brothers, They are an Enemy of Spider-Man, Spider-Woman and the Avengers.
Victim of an ancient family curse, Jack Russell struggled for years with his bestial alter-ego. But over time has conquered his inner demons. Now he fights the dark forces that plague our world. He is an enforcer of justice, an avenger of shadows, and a Werewolf By Night.
Nekra can change her angry emotions into super strength, endurance & resistance to injuries.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, which he could have prevented, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became the Amazing Spider-Man!
A criminal mercenary and assassin for hire, operating mainly on the West Coast of the United States. He was killed by the Scourge.
A journalist whom worked for the Los Angeles Courier before he became the circulation manager for the Daily Globe Newspaper
A geneticist from the 1930s who became obsessed with further evolution experiments which he used on himself. Depending on what he hopes to gain from whatever his current experiments are, he has been a force for the greater good, and for his own dark purposes.
Laura Brown is a S.H.I.E.L.D. agent and one time girlfriend of Nick Fury.
A scientist and father of Spider-Woman
A mind controlling villain, who hasn`t appeared all that much.
Gifted with the power to control the elemental forces and energies that govern the weather, ranging from the nervous system and elements present within living beings to planetary atmospheres and the depths of space, Ororo Munroe also known as Storm or The Hadari Yao is an Omega Level Mutant and Wakandan goddess, solidifying her place as one of the strongest members of the X-men and one of the most powerful beings on Earth.
Cain Marko, also known as the Juggernaut, is the step-brother of X-Men founder Charles Xavier and the avatar of Cyttorak. Powered by the Crimson Gem of Cyttorak, Marko is bestowed virtually limitless brute strength and durability which he mostly uses for criminal pursuits and wanton destruction. The Juggernaut is considered one of the strongest and most powerful beings on Earth.
Piotr Rasputin is a Russian mutant who possesses the ability to transform his body into organic steel, giving him immense strength and durability. Colossus is among the physically strongest X-Men, and is a talented artist.
A mutant and original member of the X-Men, Warren received his angelic wings at a young age along with a unique healing factor in his blood. After being twisted into a weapon of Apocalypse, Warren became the cold and distant Archangel. In the years since then, he's gone back and forth between his two identities.
Fascinated by superhuman powers, the mad genius known as Doctor Malus will go to any lengths to satisfy his curiosity. He has personally created many superhumans, and is responsible for much of the Power Brokers' work in giving people superpowers.
Nicholas Joseph Fury served in World War II as the leader of the Howling Commandos. He later became an agent, and eventually director, of S.H.I.E.L.D. Fury is one of the greatest strategic minds in the world, a born leader and a master of espionage. He currently serves as a replacement Watcher.
Viper is the former terrorist leader of HYDRA and an enemy of Captain America, Nick Fury and Wolverine among many others. While she is not the ruler of Madripoor, she did - or does - own it.
Formerly known as Gypsy Moth, Skein is a telekinetic who prefers fabrics.
A crook and companion to the Thunderbolt Songbird, after his death, she started a new life as a hero.
A first man, who was called The Gamesman was Timothy Braverman a one time lover of Spider-Woman. After he was captured, Calvin Felder took over his identity.
Harlan Krueger was a psychopathic vigilante who dressed like an executioner, used a scythe and hangman’s noose, who murdered those he saw as criminals and kidnapped women to protect them.
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