I'm tired of seeing writers who just flat out don't understand what the whole point of Spider-man is (looking at you One More Day, Sins Past, Clone Saga, etc.) I'm here to explain what you people (the writers) need to understand about our Friendly Neighborhood Spider-man.
Don't make Spider-man's life a living Hell. I honestly can't stress this enough. Making Spider-man's life a Spanish novela is absolutely pointless. It doesn't make Spider-man grow as a character, all it does it prevent him from doing so. If anything, it'll just give him some serious psychological problems. It doesn't even allow us to take Spider-man seriously if he's always moping and crying about everything, which brings me to my next point...
Don't make Spider-man a total joke, the man is how old? Oh yeah, 28. You can make Spider-man funny, just don't overdo it. For example, in Marvel NOW, Spider-man was fighting these villains and one of them had the power to unravel your clothes and this happened:
This is probably not a good way to bring back your friendly neighborhood Spider-man back after being abused for a year by a 60 year old man who gets his kicks from young people.
Spider-man is a character who should be allowed to have both his high points and his low points, not to be a nervous train wreck. He should be someone we can relate to and cheer on when he accomplishes something great! Not only that, but he should grow and flourish. When he has a wife, don't just retcon it, keep going with it. Let him start a family, let him be happy, like we want him to be.