Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
J. Jonah Jameson is the former employer of Peter B. Parker and remains an aggravate of Spider-Man. He was once the chief editor and publisher of the Daily Bugle, a New York newspaper, and the mayor of New York before his resignation amidst scandal resulting from Superior Spider Man and the Goblin Nation. He now is a host of a show on the F.A.C.T. News Channel
Peter Parker's aunt-by-marriage and one of the most important people in his life.
Editor-in-Chief of the Daily Bugle, and perhaps the best friend to J. Jonah Jameson.
Harry Osborn is the best friend of Peter Parker, the Amazing Spider-Man. His father is Norman Osborn, a global industrialist and billionaire.
Betty Brant started as a personal secretary at the Daily Bugle and later became a top reporter. Betty is also one of the many love interests of Peter Parker and ex-girlfriend of Flash Thompson
Spider-Man villain with Hydrokinesis (the ability to control water), often part of teams with vendettas against the wall-crawler. Embodies the literal opposite of Spidey's other foe, Sandman.
Former New York City Police Department officer and Peter Parker's ex-girlfriend. She was briefly transformed by the Goblin Serum, but has since been returned to normal.
Harry Osborn's fiance who absorbed a unique variation of the Goblin Serum that allows her to shapeshift into a goblin. After losing those powers, she assumed the persona of Queen Cat.
Rumor monger and scandal sheet printer, Dexter Bennett became the latest owner of the Daily Bugle after a hostile buyout of long-time owner J. Jonah Jameson.
A genius chemist who invented a potent multi-polymer adhesive and immediately decided to use his invention to commit crimes. First assuming the identity of Paste-Pot Pete, he changed it to the more intimidating name of the Trapster.
Mary Jane Watson is a major love interest of Peter Parker aka Spider-Man. She married him but didn't(!), now she's one of the few people who know who he is, and still supports him as a close friend and confidante. Currently, Mary Jane and Peter have reconciled their relationship and she no longer seems to work for Stark Industries.
Spot is a teleporting character who is usually considered to be a Spider-Man and Daredevil villain.
A long time member of the Enforcers and one of the oldest foes of Spider-Man. Ox, as his name suggests, was the powerhouse of the team. There have been two people named Ox, they where brothers.
Jackpot is a new registered hero with The Initiative who fights in New York City. There have been two people to take the Jackpot identity, Alana Jobson who died, and first and current heir Sara Ehret.
D.A. turned-Mayoral Candidate Bill Hollister. Father of Harry Osborn's girlfriend, Lily.
Junkie who hangs out at the homeless shelter where May Parker volunteers.
A man who would later take the name of Martin Li, was given an experimental drug which eventually allowed him control of some type of black electrical energy resembling a photographic negative.
A police officer in New York. Doesn't have faith that Spider-Man is a good guy.
A long-lived mutant with the rage of a beast and the soul of a Samurai, James "Logan" Howlett's once mysterious past is filled with blood, war and betrayal. Possessing an accelerated healing factor, keenly enhanced senses and bone claws in each hand (along with his skeleton) that are coated in adamantium; Wolverine is, without question, the ultimate weapon.
During World War II, Steve Rogers volunteered to receive the experimental Super-Soldier Serum. Enhanced to the pinnacle of human physical potential and armed with an unbreakable shield, he became Captain America. After a failed mission left him encased in ice for decades, he was found and revived by the Avengers. Later joining their ranks and eventually becoming the team's leader.
After ingesting an experimental super-soldier formula, the lowly Robert Reynolds became the Sentry. At least in his mind.
In constant battle with his dark side known as the Void, the Sentry has been forgotten and dead, he has resurected an vanished.
Even if he is one of earth's greatest hero, he is more the world's greatest danger.
Tony Stark was the arrogant son of wealthy, weapon manufacturer Howard Stark. Tony cared only about himself, but he would have a change of heart after he was kidnapped by terrorists and gravely injured. Pressured to create a weapon of mass destruction, Stark instead created a suit of armor powerful enough for him to escape. Tony uses his vast resources and intellect to make the world a better place as The Invincible Iron Man. Stark's super hero identity led him to become a founding member of the Avengers.
Dr. Stephen Strange was once a gifted but egotistical surgeon who sought out the Ancient One to heal his hands after they were wounded in a car accident. Instead, the Ancient One trained him to become Master of the Mystic Arts and the Sorcerer Supreme of Earth.
Simon Williams was made into a being of pure ionic energy by Baron Zemo, becoming the impossibly powerful Wonder Man. Meant to aid the Masters of Evil in their campaign against the Avengers, Wonder Man found himself sympathizing with the heroes and joined their team instead. He has remained an Avengers mainstay ever since, despite his constant insecurities and battles with his own mortality.
Namor the Sub-Mariner is the ruler of undersea Atlantis. The offspring of a sea captain and an Atlantean princess, he has been both a hero and a villain to the surface world. Namor is one of Marvel's oldest published characters with his origins in the Golden Age of comics.
The Venom symbiote bonded with Spider-Man during his adventure in the first "Secret Wars" on the Beyonder's makeshift planet called Battleworld. Initially, he thought the symbiote was just a costume. However upon his discovery that it was sentient, he rejected it. Since then, the symbiote has bonded with several different hosts. It's current host is Eddie Brock.
During an experiment Dr. Curtis Connors accidentally turned into a ferocious reptilian monster who seeks to turn humans into lizards like himself. The Lizard is one of Spider-Man’s oldest and deadliest foes while ironically, his alter ego is a close friend and former teacher of Spidey’s alter ego Peter Parker.
After his family was killed by the mob, U.S. Marine Special Forces veteran Frank Castle vowed to avenge their deaths and became a one-man army in his personal war against the criminal underworld. With a distinct death's head skull adorning his chest, Frank Castle became the vigilante known as the Punisher.
James Sanders was a member of the Squadron Sinister known as Whizzer until he pursued a solo life of crime as Speed Demon. He eventually found himself a member of the Thunderbolts despite being unsure if he even wanted to reform.
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