Well when the times does come, will all of those characters that are known to be around at that time will they be around? Like will Miguel be Spiderman during that year, or will they barely even age most of the characters we have now? Like x-men was made in the 60's, and 50 years later  Cyclops is in his late 20's, early 30s.
 
Of course no one could really know what could happen eighty years from now, but it makes me curious to see if these future characters will actually be used when the actual year comes for us.

Like, if they the future "on going" Spider-man titles will feature Miguel OHara? That would be pretty neat :)
But I don't think our world will be as futuristic as the Marvel 2099 universe :P
 
But I guess they'll still have Peter Parker, Steve Roger, Matt Murdock or Scott Summers around by then... Thanks to never-aging heroes or reboots!

The way things are, I don't see them appearing. They might be referenced though.

The timeline will magically be retconned into an alternate future.

Interesting question.

It'll be retconned into Spider-Man 2199. 
I don't think our present characters will age at all.

@Meteorite said:

The timeline will magically be retconned into an alternate future.

This