Spencer Smythe appears in 69 issues.
Alistair Smythe is the son of Spencer Smythe: a mad scientist responsible for the creation of Spider-Slayers; robots designed to hunt and kill Spider-man. After his death Alistair carried on his work.
Spencer Smythe made the belt of the chameleon, which helps him to change his face much faster.
Spencer Smythe and Jameson were trying to capture Spider-man together, ussing the Spider slayers
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