Slithe is the leader of the evil mutants of Third Earth and commands both Monkian and Jackalman. However all three were pawns to Mumm-Ra. Slithe was the most intelligent of the Mutants and was a skilled combatant and machine user also possessing enhanced strength, durability and speed.
Renamed as Slythe, he returns in the 2011 remake of the Thundercats where he is a general of Mumm-Ra's Lizard Army. Slythe's motivation is to end the ancient conflict between the Lizardmen and the Thundercats with a Lizardman victory. This incarnation usually wields an assault rifle equipped with a bayonet.
Slythe is a prominent character from the beginning of the series, first appeared leading the Lizard Army conquering Thundera. Mumm-Ra tasked him to hunt down Lion-O's company throughout the Season.
Slithe was tasked of finding 2 new generals after the loss of Grune and found Kaynar (Jackalman) and Addicus (Monkian), bringing forth a more modern version of the evil mutants. Slithe is extremely intelligent and cunning as he was one of and is now the head general of Mumm-Ra's army.