Shondra first met Bruce Wayne when his anxiety and inability to relax prompted him to visit her clinic. She was Bruce's doctor when Bane broke his spine later on, and the two began to develop a romantic relationship.
One night, Shondra visited another of her paralyzed patients, Jack Drake, at his home next door to Wayne Manor. During her session with Drake, a group of armed men kidnapped her and Drake. Bruce was heading over to the Drake residence in his wheelchair when he spotted the armed men. Though he did his best to stop them, he ended up beaten.
Though he now had both broken spirit and a broken body, Bruce went on to find Shondra. She was held hostage by her brother Benedict Asp in London. It is revealed that Asp and Shondra, whose real name is Sandra Asplin, used to work together with Asp working as an amplifier that can increase her powers. Asp used Shondra's powers to kill a small English village. She was treated with many drugs by Asp and when Bruce arrived he found himself caught between a telekinetic war between Asp and Shondra. The energy released during battle healed Bruce's back and he defeated Asp, but the intensity of the battle combined with the drugs forced on her by Asp caused Shondra's mind to regressed back to childhood. Bruce arranges to have Shondra put in a mental institution. He leaves England alone as Alfred wanted to stay in England.
In Hush, Oracle mentions that Shondra had gotten better. She made a cameo appearance as one of the surgeons working on Bruce's injured body.
Because her mind regressed back to childhood, it is likely that she doesn't remember much of Bruce or their previous relationship.