Sasuke Retrieval Arc
During the Sasuke retrieval arc, Sakon and three other members of the sound five arrived in the Leaf Village to give a proposal to Sasuke. Sasuke agreed and before setting off, Sakon helped seal Sasuke in a transformation coffin. Like the other members, Sakon has the cursed seal.
During the escort The Current Sound Four ran into the Sasuke Retrieval Squad: Naruto, Shikamaru, Neji, Kiba, Akamaru, and Chouji. Sakon went on ahead with Tayuya when Jirobo and Kidomaru decided to stay behind and fight. Kiba, Shikamaru, Akamaru, and Naruto caught up with them. Akamaru attacked Sakon only to get pulverized. Kiba tried to save him. At tht moment, him, Akamaru, and Sakon got caught in an explosion and all three were blown into a conyon.
They all survived, and Kiba and Akamaru battled Sakon. Sakon then revealed he has a brother: Ukon. Who inhabits his body. Ukon stepped out of Sakon's body and it was now two on two. Sakon and Ukon then both went into the second stage of the cursed seal. Kiba and Akamaru tried to defeat them with fang over fang, but that failed. Then they tried a new attack called Man Beast Transformation Combo. Where they turned into a giant two-headed white wolf. Using Wolf Fang over Fang the wolf spiraled blindly, missing both times it was used. Sakon and Ukon then summon a giant door called the Rashoman. When Kiba and Akamaru use their final Wolf Fang over Fang they make a dent in it.
Ukon and Sakon took this oppurtunity to try and get Akamaru and Kiba, but it didn't work when Akamaru peed something like acid on Sakon's face. Causing to go wash his face in the river. Ukon showed Kiba his and his brothers ability to meld into another's body, and then take it over through genetic and cellular manipulation. Wanting to kill Ukon then get his body taken over, Kiba struck himself with his kunai in a vital spot. Forcing Ukon out of the body. Kiba and Akamaru were in bad shape, and had to escape. They tried one last move and then fled into the river. Ukon and Sakon tracked Kiba and Akamaru to about a few miles down the river. Sakon had to rest in Ukon's body for the first time. Ukon was about to kill Kiba and Akamaru when Kankuro jumped in and used his puppets to save Kiba and Akamaru, and kill Sakon and Ukon.