Sai appears in 206 issues.
Orochimaru's former right hand man. Now one of the major villains in the story. Helping Tobi create an army against the shinobi alliance.
Kakuzu is a greedy bounty hunter. He does not like having a partner because he is prone to violent outbursts in battle that have claimed the lives of his partners, however his new partner is special.
Orochimaru is an evil Sannin who killed the third Hokage, his sensei and took Sasuke under his wing in order to make him strong and thus steal his body. After the deaths of his parents, Orochimaru became obsessed in learning forbidden jutsu. While still in Konoha, he had an apprentice named Anko Mitarashi. He also conducted an experiment on the lives of sixty newborn infants, injecting them with Hashirama Senju's cells. He was once a member of the Akatsuki organization, partnered with Sasori.
The mysterious and powerful leader of Akatsuki, a band of S-rank missing-nin. He possesses the Sage's revered Rinnegan, the eyes of reincarnation. A student of the Toad Sage, Jiraiya, and a descendant of the Uzumaki clan.
Sasuke was almost ambushed by Sai, when Sai was trying to kill him.
Suigetsu is from the Hidden Mist village and was being trained to be one of the Seven Swordsmen. He now wields Zabuza's sword.
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