Resident Evil: Degeneration, known in Japan as Biohazard: Degeneration, is the first full-length motion capture CG animation feature film based on Capcom's Resident Evil video game series. The film was made by Capcom Studios in cooperation with Sony Picture Animation and Sony Pictures Entertainment. It premiered in Japan on October 11, 2008 at the Tokyo Game Show, and was released nationwide one week later on October 18.
Unlike the live-action Resident Evil film series, Degeneration is set within the same continuity as the original video game series. The main characters Leon Kennedy and Claire Redfield appear together in this film for the first time since 1998's Resident Evil 2 video game. The movie takes place between the events of Resident Evil 4 and Resident Evil 5.
The survival horror saga continues in this original, computer animated feature film inspired by the popular Resident Evil series of video games and films. Seven years after Leon S. Kennedy and Claire Redfield fought the sinister Umbrella Corporation in Raccoon City, Harvardville Airport has been overrun by zombies. Now, as the deadly G-virus is released, and a mutated creature embarks on a terrifying rampage of death and destruction, Leon and Claire must race to eliminate the virus, defeat the monster, and do battle with a rogue soldier intent on seeking vengeance for the loss of his family back in Raccoon City. With the fate of the entire world hanging in the balance, Leon and Claire race to ensure that the biohazard is contained, and prevent history from repeating itself.