During the early Pendulum Wars, almost a century before the Lambent Pandemic, the COG established the New Hope Research Facility to study the possible toxicity of Imulsion. Because of the discoveries made there, the facility was shut down and the scientists as well as a large number of test subjects were forced to relocate to Mount Kadar. Myrrah is a descendant of these scientists and, unlike the New Hope subjects, is completely human.
Gears of War
"I'm pleased with our progress. I understand they have located another squad. Our strategy remains the same. Cut off the head of the Snake and the body dies. We will win this war. It's only a matter of time."
In the Lightmass Offensive, Queen Myrrah is behind the scenes and never on screen, narrating to the player from a Locust Horde perspective when General RAAM attacks the Delta Squad pick up in Ephyra, resulting in the death of Minh Young Kim, and then again after the Lightmass Bombing in Timgad Valley is successful for the COG.
When she first narrates, she is confident in the success of the Locust forces in the war, and following the detonation of the Lightmass bombs, she states that the Locust Horde cannot stop fighting and will not stop fighting until they either win or become extinct.