I mean he's been shot and stabbed God only knows how many times now and is still walking. He's been hit by people who have gone toe to toe with Thor and has walked away from it. Although him fighting spectre is quite a bit of PIS.
Frank getting shot several times and still kicking ass like it's nothing.
Frank getting hit by people that have fought Thor before and no Garth Ennis didn't write these stories.
So this begs the question is frank the toughest nonsuperhuman SOB in comics when it comes to pain tolerance?