Character » Psi appears in 24 issues.
Alexandra Danvers is a bio-engineer of the D.E.O. and the adoptive sister of Supergirl.
Originally a shock-jock, Leslie Willis is turned into electricity-based super villain known as Livewire.
Nekron is the embodiment of death and darkness. He has the power to take and restore life as he pleases, contributing to the reanimation of many heroes in the past. Nekron has also recently become the leader and creator of the Black Lantern Corps, making Nekron the harbinger of the Blackest Night.
Reign is a Worldkiller created by a group of Kryptonian scientists. She and her fellow Worldkillers became enemies of Supergirl when they attempted to conquer Earth.
Imra Ardeen is a founding member of the Legion of Super-Heroes in the 30th and 31st centuries under the code name Saturn Girl. Though all of the inhabitants of her homeworld of Titan are telepaths, Imra's telepathy ranks among the strongest of her race. Saturn Girl is the first ever female character to lead a super-team in comic book history.
Supergirl has been introduced several times, and with different back stories each time. Each Supergirl is focused on individually and their aliases are listed.
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