That's an excellent question...
What the new ones are supposed to be about... No idea... But...
Uncanny X-Men - The first. Charles Xavier, Professor X, brought to his mansion five young mutants to train them in the use of their powers. Cyclops, Jean Grey (Marvel Girl), Angel, Beast, and Iceman. It's change quite a bit over the years, but Uncanny X-Men, I believe, is the mainstay of all the X-Men series.
New Mutants - After Professor X had been training the original team for a few years, he brought even younger mutants to his mansion and officially turned it into a school... Cannonball, Mirage, Karma, Sunspot, Wolfsbane, Magman, and Cipher. Later Magik and Warlocke would join them.
Astonishing X-Men - Um... This series seems to have story arcs that the rest of the Marvel Universe is NOT involved in. Things like the X-Men fighting on Break World, or the Ghost Box series...
X-Men - This seems to have the same purpose as Astonishing X-Men. There's so much going on with the X-Men, that you need several series to tell the whole story...
After those, it gets fuzzy... But even though there are a number of titles, they run parallel to each other.
X-Force - at least the last two volumes of X-Force were teams put together to basically kill... They do that which no one else really wants to do... and they are clandestine. Scott formed the second X-Force team (Wolverine, Warpath, X-23, Angel, and Psylocke) to go after and kill the purifiers... The latest X-Force team was put together by Wolverine without Scott's knowledge (Wolverine, Angel, Psylocke, Deadpool, and Fantomex)
Legacy - SEEMS to try and stick to major events; Civil War, Seige, Nation X, etc...
Generation Hope - All centered around Hope Summers, the first Mutant born after M-Day. The writers are obviously forming a team that parallels the very first X-Men team... It started off very slow, but it's gotten good.
X-Factor - This is not really associated directly with the X-Men, but many of their members were X-Men at one time, or at least students at Xavier's school. I love this series.. Their stories do not tie into to the 'mutant fight for survival' every issue like most of the X-Men series do. These are simply Mutants who formed a detective agency... It's VERY good.
Wolverine - Obviously, this one is all about Wolverine.
I hope this helps.
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