TBH, the power level is very difference between the two series and comic and webcomic have different timeline. People can't use Saitama as a base. He literally punches a whole through reality to another dimension. Saying Tatsumaki can't affect people because of will is like saying why can't a regular knife can't cut Hulk. The level is just too different.
Tats stomps regardless, just the very fact that she always flies around already give her advantage in most fights. Airborne enemies tend to hard to fight, and she is continental to multi, depending on how you scale her, which is way above anyone in OP's paygrade that is at island to country at most. Luffy has no way of hurting her with how durable Tatsumaki is, tanking a continental slice at point blank.
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