X and Ghost, I've had this idea for a long time of an open world game set in the fictional city of Arcadia from the Dark Horse comics in which their are 2 main story lines one in which you play as Ghost and the other as X both of which intertwine and missions that involve them confronting or interfering with one another, say for example X marked one of the people from Ghost's past. Have the game filled with cameos and Easter Eggs towards other Dark horse cities and characters say in a mission where you got to a museum the Loki Mask is on display, including side missions where you get to play or work with characters such as Barb Wire or Monster.
One of the benefits of Lobo is that there is a quick fix/explanation for any unwanted incarnation of Lobo, that it is a clone of the original. Because one of Lobo's powers is to regenerate/clone himself from a drop of his own blood. That's really the only reasoning I can think of for this "Slobo" to be hunting down a more matured Lobo. If that turns out to be the case I think it can turn out okay but if this new Lobo is supposed to be the original and is going to kill off the Lobo we know and love, that'd be disappointing.