Just a guess here, but this irradiated bullet will most likely be the "cure" for Jane now. It will be the surprise ending. The "Jane" here is from her hammer which leads to the next issue focusing on it as the lead in the story...
Now, if this issue DOES see an end to her ailment it will be in poor taste (imo), as the Ferry cover is a prostate cancer cover.
DaymarePrime's comments