I certainly love Ron Pearlman and don't doubt for a minute that he could do it and Brad Garret was great in the cartoon. But I think the person with the best voice, attitude, sense of humor and look (if they CG'd him to look a little younger like they did to Patrick Stewart in X3) would be Hulk Hogan. I'm not a wrestle fan but he has such a wonderful Bastich voice and look and his sense of humor is very along the lines of Lobo (maybe darken up his jokes a bit so he would be even more Lobo-like)
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