Professor Oak features in the RBY series of the Pokemon Manga.
He owns every non-legendary Pokemon that lives in the Kanto region.
Professor Oak gave Red and Green both a Pokedex each, Green obtained Charmander and Red received Bulbasaur.
After accidentally releasing all of Oaks' Pokemon, Red sort out to help Oak. Hours later, Red and Oak re-captured all of the accidentally released pokemon, except one, Bulbasaur. After saving Red from a wild Machoke, Oak decided to give Red Bulbasaur.
In the anime Professor Oak is a famous scientist and poet pokémon, it was he who gave Ash Ketchum, when he turned 10 years old, his first Pokemon, Pikachu, and his grandson Gary Oak a Squirtle. May also gave a Squirtle baby.
Several of Ash's Pokémon are in their lab, such as:
- Krabby> Kingler
- 30 Tauros
- Cyndaquil> Quilava
- Chikorita> Bayleef
- Phanpy> Donphan
- Snorunt> Glalie
- Taillow> Swellow
- Treecko> Grovyle> Sceptale
- Starly> Staravia> Staraptor
- Turtwig> Grotle> Torterra
- Chimchar> Monferno> Infernape