60 years ago and young girl was kidnapped by a cult and caged with the snakes. Then something happened to the girl and she gained powers. She managed to get free from the cage and killed her captors. Then she met a demon.
Years later joined the World's End Circus, where she fit in with the other freaks. She used her psychic talent only when needed. She lied about her past and told she was a circus snake charmer.
Ophidia was kidnapped again by the cult and offered as a food for Sargoth. After the demon was summoned, Ophidia revealed her abilities, by transforming into a half-snake herself and charmed the snake-god Sargoth. She made him kill all the cult members and released the other prisoners. She then sent Sargoth back to where he came.