Nestor Redondo's first professional job was with Bulaklak Komiks. His popularity really escalated when he was commissioned to illustrate the blockbuster series 'Darna', written by Mars Ravelo in the early 1950s. By the late 1950s he was illustrating for several comic books at the same time, Pilipino Komiks, Tagalog Klasiks, Hiwaga Komiks and Espesial Komiks.
His talents were noticed by American editors from D.C. and Marvel Comics, through Tony DeZuniga.
He took over 'Swamp Thing' from Bernie Wrightson and over the years worked on just about all D.C. titles, especially 'Rima, The Jungle Girl'.
From 1972, he made comic adaptations of novels for Pendulum Press ('Davy Crockett', 'Dracula', 'Sherlock Holmes'), contributed 'Conan' stories to Marvel's The Savage Sword of Conan magazine, and worked on a variety of Christian comics.
Redondo opened a studio that featured other Filipino artists like Alex Nino, and worked on serials like 'Tarzan' and 'Ragman', under supervision of Joe Kubert .
In 1978, Redondo settled in California and started working in animation. After working on some independent projects, he moved on to do storyboards for Marvel's animation department. Redondo's comics work of the 1980s includes inking 'Aztec Ace' for Eclipse Comics, and drawing 'Solarman' for Marvel and 'Newstralia' for Innovation Comics. In 1979 he received the prestigious Ink Pot Award at the San Diego Convention.