Mr. Fantastic appears in 6160 issues.
Craving for the power of a Hulk, Emil Blonsky purposely had himself infected with triple the amount of gamma that the Hulk originally had. However, it turned him into a monstrous amphibious reptoid as being originally more than twice the strength of the normal calm Hulk, at the cost of never being human again.
Reed Richards is Mr. Fantastic, leader of the Fantastic Four, loving husband of the Invisible Woman, mentor to the Human Torch, and best friend to the Thing.
This strange looking creature attacks Mr. Fantastic and cements itself to his body.
A Skrull general.
Agent of Atlantis that battled the Fantastic Four
A geneticist who in a dystopic future was the creator of the Hound program which captured mutants wherein they were processed and used to hunt down their fellow mutants.
Chief prosecutor when the Fantastic Four are put on trial in "The Fall of the Fantastic Four" arc
Gabriel Lan is a former Herald of Galactus known as Air-walker, his best friend Pyreus Kril succeeded him as The Firelord.
Reed Richards is Mr. Fantastic, leader of the Fantastic Four.
Gregorovich is an ambassador from Russia. He opposed the Inhumans being given sanctuary on the moon.
Ling is an ambassador from China. He opposed the Inhumans being given sanctuary on the moon.
Member of Halycon sent to earth the reclaim the Cosmic Cube from the Fantastic Four.
Reed Richards is the leader of the Fantastic Four. He is a remarable scientist and has multiple super-powers.
Arch-nemesis and best friend of Adam Brashear, also known as the Blue Marvel. His power is unstable so he can only exist in our world for brief periods of time. Anti-Man was made into Galactus first Herald of Life.
Leader of the Other Side of Zero, a cult of the Negative Zone that wishes to bring the Annihilation Wave to the Positive Zone
Robot version of the Egyptian God. Member of the Pharaoh's Guard.
The Apocalypse Beast fought the Fantastic Four and Iron Man in Japan.
Arcadius is the Chancellor of the Genetics Council, determining how the Terrigen Mist should be used.
Ares is the son of Zeus and the Olympian God of War. After years of fighting against The Avengers, Thor, and mostly his own brother Hercules, Ares joined the ranks of the Avengers. He was a member of Tony Stark's official Avengers team and later Norman Osborn's Dark Avengers. After he attacked Osborn for tricking him in starting Siege on Asgard, he was stopped and killed by the Sentry.
Arishem the judge is the leader of the Celestial hosts, and second in authority only to the One Above All. He judges the worthiness of species influenced by the Celestials, deciding which planets and its species will continue to live.
The imperial ruler of the extra-dimensional world of Polemachus. More recently, Arkon found himself in Weirdworld, a strange otherworldly dimension.
Scientist Arnim Zola became one of the first biochemists in history after finding notes and equipment belonging to the offshoot race of humanity, the Deviants. He learned many things from his studies, including the ability to transfer people's essence into clones of their original bodies.
Arno briefly faced The Fantastic Four when Zarrko the Tomorrow Man brought him into the mainstream timeline to act as a distraction while he made his getaway.
A Moloid/Subterranean who battled Mr. Fantastic and War Machine.
Avius is a winged guardsman of the Inhumans.
The 13th Baron in the Zemo bloodline. Helmut followed in the footsteps of his father before him, becoming an enemy of Captain America and the Avengers. In what could be his greatest scheme ever, Helmut masqueraded as Citizen V and led the Thunderbolts to public acclaim in order to conquer the world. In the end, he failed only because his cohorts desired to remain heroes and rebelled against him.
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