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Diablo is a 9th century alchemist with aspirations of world dominance. He is able to produce any number of amazing potions that defy scientific analysis. Diablo does not seem to age. He is an enemy of the Fantastic Four.
Swindled by his business partner out of his equal share of the profits from their company, Adrian Toomes set out for revenge by using a flying harness of his own design. He has however, met defeat several times at the hands of his arch-nemesis, The Amazing Spider-Man.
MacDonald "Mac" Gargan was a failing private investigator that was turned into the Scorpion with financial help from J. Jonah Jameson. He became a host of the Venom symbiote and was part of Norman Osborn's Dark Avengers. After the US Government took the symbiote, he became The Scorpion once again.
Victim of an ancient family curse, Jack Russell struggled for years with his bestial alter-ego. But over time has conquered his inner demons. Now he fights the dark forces that plague our world. He is an enforcer of justice, an avenger of shadows, and a Werewolf By Night.
Man-Thing is a powerful swamp creature and guardian of the Nexus of all Realities. He was once human and turned himself into a monster as a last act of defense and a way too avoid his serum falling in the wrong hands.
Once Michael Morbius was a world-renowned bio-chemist, dying of an unknown blood disease and desperately searching for a cure. He found that cure, but, in turn, it afflicted him with a curse far worse than any possible disease; the curse of the blood-sucking night-beast; the curse of the Living Vampire.
The sole surviving robot of a government project, X-51 had the benefits of humanity by being raised as a son by Dr. Abel Stack. Dubbed "Machine Man", he became a superhero and later an Avenger until being corrupted by Sentinel technology and developing a strong dislike for humans. Now, he stands for all artificially intelligent beings right to be considered sentient.
Wade Wilson is a former test subject of the Weapon X program, where he received his regenerative healing factor through the scientific experiments conducted upon him. A prominent enemy, ally and later, member of X-Force. He's famous for breaking the Fourth Wall.
Samuel Sterns was a worker in a chemical plant in a menial capacity until an accident working with radioactive material bombarded him with gamma radiation, turning his skin green and making his head grow, filling it with extreme knowledge. He became the one who men call The Leader and was one of Hulk's arch-enemies.
A young woman whom encountered the Man-Thing. She became a powerful and skilled sorceress with extensive knowledge of magic and arcane lore. She is also the cousin of Johnny Blaze and Dan Ketch.
Director of A.R.M.O.R., Charles Little Sky is a mutant with the power to create portals to other dimensions.
Wilson Fisk's beloved wife, and apparent Art connoisseur.
As a result of being exposed to the Terrigen Mist when he was an infant, Gorgon developed hooved feet and a powerful lower body. His legs are so powerful that with a single stomp, he can create shock tremors to disable his opponents.
The Jackal is an enemy of Spider-Man who played a big role in both of the Clone Sagas. He has since seemingly returned to infest Manhattan with spider-powers for his own sinister ends, organizing test subjects into a spider-powered army.
A member of the Attilan Royal Family and Magister of the Tower of Wisdom. Karnak is a philosopher and master martial artist trained in the extrasensory ability to find the weakness or fault in any object, person or idea.
A member of the Inhuman Royal Family, Triton was exposed to the Terrigen Mist when he was a year old and emerged with a number of aquatic mutations.
John Kelly was the first attempt at creating a Deathlok cyborg. However, when the project failed he was killed. His brain patterns were later discovered by Michael Collins, as Deathlok, and reluctantly digitized into another cyborg body. John Kelly became the cyborg known as Siege.
Ursa Major is a Russian mutant that transforms into a giant bear. He becomes a valuable member of the Soviet Super Soldiers and the Winter Guard.
The Whizzer is a war-time superhero possessing superhuman speed. Acting as a member of the Invaders and Liberty Legion during World War II, the Whizzer continued his crime-fighting career decades after the war and even joined the Avengers.
Denying his infernal heritage, the Son of Satan uses his abilities for the betterment of mankind, but has at times succumbed to his darker, demonic side, even clashing brutally with the forces of both Heaven and Hell.
Wundarr the Aquarian is a powerful pacifist who was attached to Project Pegasus. He is friends with the Thing among others. More recently, he proved to be the only person ever to be bitten by a Marvel-Zombie and live to tell the tale, purging the disease out of his body.
Deadpool from Earth-2149 who ended up in Earth-616. Currently only a head, and a member of Deadpool Corps.
Member of The Command, the Initiative team of Florida.
Captain Mexica is an alternate version of Captain America from a reality where the Aztec Empire never fell.
Ben Grimm, better known as the Thing, is the original quintessential tough-guy of the Marvel Universe. But, because of his transformation, he's also the tragic member of the Fantastic Four. Ben was an ace test-pilot until exposure to intense cosmic radiation mutated him into a rock-skinned monster with immense superhuman strength. Ben's exterior is much harder than stone which gives him a rather gruff disposition; but deep down, he has a heart of gold.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became Spider-Man.
A social worker turned hero, Sam Wilson's bleak outlook on life was wiped away the day he met Captain America. Using a winged costume and his remarkable combat prowess and avian telepathy, he became the Falcon - defender of Harlem, and eventually bearer of Captain America mantle.
Tony Stark was the arrogant son of wealthy, weapon manufacturer Howard Stark. Tony cared only about himself, but he would have a change of heart after he was kidnapped by terrorists and gravely injured. Pressured to create a weapon of mass destruction, Stark instead created a suit of armor powerful enough for him to escape. Tony used his vast resources and intellect to make the world a better place as The Invincible Iron Man. Stark's super hero identity led him to become a founding member of the Avengers.
Dr. Stephen Strange was once a gifted but egotistical surgeon who sought out the Ancient One to heal his hands after they were wounded in a car accident. Instead, the Ancient One trained him to become Master of the Mystic Arts and the Sorcerer Supreme of Earth.
The world knows Wanda Maximoff as the Scarlet Witch, with probability manipulation and reality-warping abilities. The twin sister of Quicksilver, mother to Wiccan and Speed, and ex-wife of the Vision; Wanda has taken on many roles throughout her life but will forever be known for causing the Decimation.
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