Comicdom's #1 non-team is back, and they've never been better! Hulk, Dr. Strange, Sub-Mariner, Valkyrie and Nighthawk team with Luke Cage, Daredevil and Son of Satan to take on the likes of the Wrecking Crew, Satannish and Asmodeus! Then, spinning out of MARVEL TWO-IN-ONE, comes Steve Gerber! Deconstructing genre conventions with a healthy dose of absurdity, Gerber's innovative Defenders run turned readers' expectations on their heads - so suitably we're including the original Atlas Era appearances of the Headmen: Gorilla Man, Jerold Morgan and Chondu the Mystic! Topped off with a GIANT-SIZE battle royale with the Grandmaster and a Squadron Sinister rematch, this one is a MARVEL MASTERWORKS if there ever was! Collecting DEFENDERS (1972) #17-21, GIANT-SIZE DEFENDERS #2-4, MARVEL TWO-IN-ONE #6-7; and material from MYSTERY TALES #21, WORLD OF FANTASY #11 and TALES OF SUSPENSE (1959) #9.