Marco Renna was born in Brindisi in 1989, he remained there until 2010, when he moved to Bologna.
He graduated from the International School of Comics of Reggio Emilia. Later, in collaboration with some writers he published some short stories for the digital magazine Sbam! Comics and for Future Quake Press on Something Wicked. In 2015 he made his debut in the American market as the penciler for Action Lab Comics for an issue of Actionverse and for the The F1rst Hero: Wednesday's Child mini-series.
In 2016 he won the Top Cow Talent Hunt as a Runner-up.
Currently he works for Aspen Comics as a penciller for the series All New Micheal Turner's Fathom.