Spinning out of the comic-book adaptions of 2001: A Space Odyssey. After Marvel lost the license to publish the series, they brought their own creation, Machine Man, to the Marvel Universe and gave him his own series.
The first (and longest) series is known for it's classic Jack Kirby art. The series lasted untill issue 9, but was revived some months later with issue 10 and a new creative team. The series is famous for introducing villain Jack O' Lantern, as well as the second appearance of Alpha Flight.
After this series ended with issue 19, Machine Man returned with a Machine Man mini-series in 1984 and returned with an ongoing series called X-51, starring the Machine Man.