Born of Edgar Pierre Jacobs’ imagination during the post-WWII period, Professor Philip Mortimer, nuclear physicist, and Captain Francis Blake, dashing head of MI5, are legendary heroes of the Franco-Belgian industry. The author, a close collaborator of Hergé, appreciated the excessive and the astonishing that could be found within the scope of scientific invention; his heroes, very much ahead of their time, discover extraordinary objects and phenomena through their uncommon adventures. Before devoting himself exclusively to them, Jacobs collaborated with Hergé and took part in the making of “Tintin in the Congo”, “Tintin in America”, “The Blue Lotus”, “King Ottokar's Sceptre", "The Seven Crystal Balls", and the "Prisoners of the Sun". Following Jacobs' death, his incomplete second volume of Les 3 Formules Du Professeur Satō was finished by his friend Bob De Moor and later the series was continued by two author/illustrator teams alternating albums, the first led by Jean Van Hamme (later Jean Dufaux) with Ted Benoît (and later René Sterne, Chantal De Spiegeleer and Antoine Aubin) and the second by Yves Sente with André Juillard.
Initially published by Le Lombard until 1982 when the exclusive Les Éditions Blake et Mortimer was created.
A 26 episode animated series was produced in 1997, adapting the first nine storylines, and four additional original ones.