Prime Earth (Earth-616)
Karla Faye was contacted by Matthew Murdock to ask about her murdered son Bradley. She was beaten by her husband but remained loyal to him, and even accused Daredevil of beating her husband.
Years later she needed to be saved by Daredevil from the husband she defended.
Marvel Cinematic Universe (Earth-199999)
Karla Faye appeared in Episode 13 of the 2nd season of Marvel's Agents of S.H.I.E.L.D. She was portrayed by Drea de Matteo. Her character differs from her comics incarnation in that she had no ties to Daredevil and was an "enhanced" individual with razors grafted to her fingertips. She was defeated in combat by Bobbi Morse.