Kaguya Ōtsutsuki appears in 41 issues.
Ashura Ohtsutsuki is the youngest son of the Sage of Six Paths who believed love is the path to true peace. His line would go on to become the Senju and Uzumaki Clans.
Younger son of Kaguya Ōtsutsuki and brother to the Sage of the Six Paths, with whom he fought and sealed the Ten-Tails. He wielded the Byakugan and went on to become the ancestor of the Hyūga clan, as well as the founder of the Shinobi of the Moon.
Indra Ohtsutsuki is the eldest son of the Sage of Six Paths. He believed that power was the way to peace. His line would go on to become the Uchiha Clan.
Hagoromo Ōtsutsuki is the first human born with the ability of chakra. He became the legendary priest monk known as the Sage of the Six Paths. He defeated the Ten Tailed Beast and separated it to create the nine Tailed Beasts.
Zetsu is a living organism that Madara Uchiha created from the Demonic Statue of the Outer Path and Hashirama's living clone. His dark half was imbued with the manifested will of Madara.
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