Kaguya Ōtsutsuki appears in 39 issues.
Younger son of Kaguya Ōtsutsuki and brother to the Sage of the Six Paths, with whom he fought and sealed the Ten-Tails. He wielded the Byakugan and went on to become the ancestor of the Hyūga clan, as well as the founder of the Shinobi of the Moon.
Kakashi Hatake is a ninja of the Hidden Leaf Village and the Jonin leader of Team 7. With the Sharingan Eye, he can copy any jutsu he sees. He was the Leaf Village's sixth Hokage. His Teacher is the Fourth Hokage, Minato. His Father is the White Fang of the Leaf, Sakumo. His rival is Might Guy and his best friend is Obito Uchiha. Before becoming leader of Team 7, he joined the Hidden Leaf's Anbu and befriended Yamato, a fellow Anbu and comrade.
Kinshiki is a member of the Otsutsuki clan, a clan of celestial beings and is the second antagonist of Boruto: Naruto the Movie.
Momoshiki Otsutsuki is the main antagonist of Boruto: Naruto the Movie. He is a member of the Ōtsutsuki Clan.
Naruto Uzumaki is a hyper-active ninja of the Hidden Leaf Village and a member of Team 7, son of the Fourth Hokage and Kushina Uzumaki. Shortly after his birth, the Nine-Tailed Fox was sealed inside of him, but this was kept a secret from him for years. He has now achieved his dreams and became Konoha's Seventh Hokage. He also has a wife and two children.
Hagoromo Ōtsutsuki is the first human born with the ability of chakra. He became the legendary priest monk known as the Sage of the Six Paths. He defeated the Ten Tailed Beast and separated it to create the nine Tailed Beasts.
Sakura Haruno is a bright and energetic ninja of the Hidden Leaf Village, and a member of Team 7 as their medic. She is now the wife of Sasuke Uchiha and mother of Sarada Uchiha. She was trained by Tsunade, the Fifth Hokage, in both medical jutsu and combat.
Sasuke is a anti-hero in the Naruto series. He is the lone survivor of the Uchiha Clan from the Leaf Village and former member of Squad 7. He betrayed the Leaf Village to follow his own obsession with revenge. After his battle with Naruto at the end of the series, he regretted his past actions and chose to travel the land and eventually became a key protector of the Leaf Village.
Tobi, born under the name of Obito Uchiha, is the true true leader of the Akatsuki. He was part of a Genin team with Kakashi and Rin and trained by the Fourth Hokage, Minato. Thought dead and after witnessing the death of his beloved Rin, he was saved by Madara Uchiha and chose to turn his back on his village and take over the world. He was the Jinchūriki of the 10 tails.
Tsunade is one of the three legendary Sannin. Granddaughter of Konoha's first Hokage. She's an expert in medical-ninjutsu with powerful, raw and physical strength. She was the Leaf Village's fifth Hokage followed by Hatake Kakashi as the sixth Hokage. Her Teacher was the Third Hokage, Hiruzen Sarutobi.
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