Izuna Uchiha appears in 10 issues.
Butsuma Senju was the harsh father and ninja master to his three sons Hashirama, Tobirama, Itama.
Hashirama Senju was the leader of the Senju clan that founded the Hidden Leaf Village along with Madara Uchiha and the Uchiha clan. Hashirama went on to be the First Hokage. He is the older brother of the Second Hokage, Tobirama, and the grandfather of the Fifth Hokage, Tsunade. He was the strongest shinobi of his time, and hailed as the "God of Shinobi", and the only known natural user of Wood Style.
Tobirama Senju was the Second Hokage, after the death of Hashirama, his brother and the First Hokage. He was a pragmatic leader who valued loyalty, to the village, above clans and is the second most powerful Hokage their ever was. Before his death, he chose Hiruzen Sarutobi as his successor as the Third Hokage. He created many techniques, such as: Shadow Clone Jutsu, Flying Thunder God Technique and Summoning: Impure World Reincarnation.
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