Itsy Bitsy appears in 12 issues.
A new villain whom was part of the Hateful Hexad. He was killed by Itsy Bitsy during a robbery.
Wade Wilson is a former test subject of the Weapon X program, where he received his regenerative healing factor through the scientific experiments conducted upon him. Deadpool's powers and personality traits combine to make a wild, mentally unstable, and unpredictable mercenary. Deadpool has been a member of X-Force and the Thunderbolts, and a self-professed member of the X-Men and the Avengers. The "Merc with a Mouth" is infamous for breaking the fourth wall.
The Gibbon's unsuccessful attempts as a criminal and a hero branded him a loser. As a mutant, he retained his powers after "M-Day."
A long time member of the Enforcers and one of the oldest foes of Spider-Man. Ox, as his name suggests, was the powerhouse of the team. There have been two people named Ox, they where brothers.
Peter Parker was bitten by a radioactive spider as a teenager, granting him spider-like powers. After the death of his Uncle Ben, which he could have prevented, Peter learned that "with great power, comes great responsibility." Swearing to always protect the innocent from harm, Peter Parker became the Amazing Spider-Man!
A former Nazi scientist, von Meyer's expertise in cosmic radiation allowed him to mutate a colony of bees, thus becoming Swarm. As Swarm, von Meyer's body is completely made of bees.
Deadpool's friend/henchman, technology expert and weapons dealer. More recently he wanted revenge against Deadpool for being a lousy friend. He was killed and, in the afterlife, struck a deal with Mephisto as Patient Zero.
The White Rabbit is a young woman with a dangerous obsession with Lewis Carroll.
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