Peter Parker's former mentor, Dr. Connors, next experiment gone array resulted in the Iguana. Dr. Connors bestowed a normal iguana with his memories and empowered him with the super powers of the Lizard creating the mutated reptile Iguana. The Iguana then went on to fight Spider-Man at Doctor Connor's lab at Empire State University.
Amazing Spider-Man - Iguana is set to appear in the upcoming game for the Amazing Spider-Man movie. Iguana will be a test iguana used in Dr. Curt Connors which turns it into a monster for Spider-Man to stop as a boss battle.