Originally a cow living in Switzerland over 300 years ago, Bessie was bitten by Dracula one night when she could not find any human to feed on. The next morning her owner found her dead and buried her. Three days later however, she rose from the grave Hell bent on revenge towards Dracula and his kind.
During it's adventures it encountered Man-Thing and Howard the Duck. Although she was staked at the end of this adventure with Howard and the Man-Thing, more recently she was seen alive and well when she met Deadpool, the Merc with a Mouth.