Guile appears in 119 issues.
Abel is a french Mixed Martial Arts fighter with no recollection of what happened to him. It's later known that he happens to be a failed replacement body for M. Bison that gained sentience.
A wrestler born in New York, Alex enters the World Warrior tournament to avenge his mentor and father figure, who got badly hurt by Gill. After that, he went on to hone his skills and find worthy opponents.
Amy is the daughter of Guile and Julia, niece of Eliza Masters and cousin of Mel Masters.
Guile is an ally of Cammy against Shadaloo. In the 1994 Street Fighter movie, Cammy is Guile's second-in-command.
Charlie Nash is a former Captain of the U.S. Air Force, and best friend to Guile. He stood up against Bison, only to be shot by his own team. He is later ressurected to continue his vendetta.
Chun-Li is a martial artist deeply rooted in the Chinese Kung-Fu and an Interpol agent with a score to settle with M. Bison and Shadaloo over her dad's disappearance. Known as 'The Strongest Woman in The World' in-universe.
Dhalsim is a Hindu ascetic and practitioner of Yoga who travels the globe participating in street fighter tournaments to earn money for his family and his impoverished village.
A german descendant mercenary, D. Dark was originally a soldier under the command of Guile. He was ambushed by Rolento's soldiers and his whole unit wound up dead. D. Dark now seeks the heads of Rolento for killing his comrades and Guile for not preparing them enough for the fight.
The warrior princess of an African tribe that has a cultural tradition of fighting, Elena is a skilled combatant who practices the Brazilian art of Capoeira.
The secretary of Guile at San Francisco
Julia is Guile's wife and sister of Eliza Masters.
Ken and Guile are brothers-in-law.
Rolento was a member of the Red Berets, responsible of protecting the drug production of some gangs in Metro City. He was later introduced in the Street Fighter Series, trying to create his utopian nation and enlisting soldiers.
Ryu is the main character of the Street Fighter series. He is one of the greatest fighters in the world. Along with Ken, he practices a fictional martial art rooted in an ancient assassination style that he learned from Gouken. He is a wandering warrior in search of becoming a "True Martial Artist".
Captain Sawada is a soldier of A.N. (Allied Nation).
Thunder Hawk is a mighty American Indian Warrior. He is superhumanly large and strong, he is an expert in grappling and ancient Thunderfoot magic.
Tom is the friend and mentor of Alex.
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