Wolfe is the no-nonsense warden of Iron Heights prison. He is secretly a metahuman with the ability to affect muscles, usually to induce severe pain in his prisoners as well as guards or superheroes who cross him. He is firmly against the idea or rehabilitation of prisoners and goes out of his way to demean the Rogues and encourages his guards to administer beating on the inmates. In his own words "This prison is not a revolving door. It is not here for your benefit. There is no rehabilitation program. No therapists to cry to about daddy's physical abuse or mother's drug dependencies. We don't care. You choose this path regardless."
Wolfe is also responsible for the inhumane treatment of the "supervillain," Fallout. In order to power the facility, Wolfe had the radioactive man plugged into the prison, painfully draining the life out of him to save on costs. When the Flash discovered this, Wolfe covered up evidence and claimed that the Flash was suffering from hallucinations due to Murmur's frenzy virus.
When the Joker used 'Joker Juice' on a number of criminals (See Joker: Last Laugh), Deadshot, Merlyn and Deadline attacked Iron Heights. Deadline went to personally dispose of the warden but Wolfe used his power to disarm the assassin and then shot him dead with his own gun.