As Gotham City swirls in a maelstrom of evil and villainy, three of the most unlikely candidates – Catwoman, Poison Ivy and Harley Quinn – step forward to bring some light to the situation. But will their efforts enough to stem the tide of madness and mayhem? Poison Ivy starts her new job at S.T.A.R. Labs Gotham City with dramatic results as she fires the whole staff. It is a mistake she may regret. Meanwhile Harley and Cat Woman looks for the culprits of several missing dogs on the streets of Gotham. Only to find out the culprit is closer to home than either one could know.