The only piece of extremely up in the air shaky implied evidence we can get to such a thing is when Phantom Stranger and the Spectre fought to a near stand still and the Voice (who is just an avatar of the Presence) stated their fight would wreck all of creation (which often times means all of existence).
Fighting Spectre is a little shaky because Spectre has as many jobbing as he does Multiversal feats. To truly scale to Spectre for Multiversality, you have to prove that the particular character you are scaling to Spectre was portraying Spectre or Multiversal or if it was a DC writer who has portrayed Spectre as Multiversal at once.
One could argue that the N52 fight of PS and Spectre was Multiversal since Presence implied it.
But the weight of Presence's statements depends on the interpretation of the type of debater you are. There are some people who think the statements of even Cosmic characters mean nothing for some reason.
I personally, if you asked me, I take the Presence's (the Voice) statement on PS being above Multiversal as true. I don't think a Cosmic character would just say shit just because.
And destroying all of Creation in DC is a way above Multiversal feat considering DC's presumed theoretical size in its Cosmology.