what would be a good what if title?

It has to be marvel (of course).

If death fell in love with thanos, and the rest played out like a 90s sitcom.

Hickman doing something other than an end of the world story.

Sentry turns out to be TOAA's long lost brother.

What if... Radiation was realistic?

What if Cyclops kept Dark Phoenix

Mantlo, Giffen and Mignola would have kept working on an on-going RR... I know its not really 'What if' as was suggested by OP but I just liked the original 4-part mini's zany feel.

What if...Cyclops and Wolverine agreed? (Schism)

What if...Rogue and Wanda talked it out? (Uncanny Avengers)

What if...Superior Spider-Man and Mary Jane did the deed? (it's there in the title, people)

What if...Loki told Leah the truth? (JIM)

What if...Captain America and Cyclops went on a bros trip? (Pre A vs X)

What if...

I'll stop. I've bored myself even worse than I've bored those who bothered to read my post.